This program explores the clinical utility and safety profile of natural micronized progesterone as a cornerstone intervention in the prevention of preterm birth. Participants will examine the latest evidence regarding its mechanisms of action, optimal delivery routes, and specific patient selection criteria for those at high risk of spontaneous preterm labor. By analyzing recent clinical trials and international consensus statements, the course equips practitioners with a standardized framework for implementing progesterone therapy to improve neonatal outcomes and reduce maternal morbidity.