Dydrogesterone in the Management of Recurrent Pregnancy Loss

Recurrent pregnancy loss (RPL) is often linked to luteal phase insufficiency, where inadequate progesterone levels fail to sustain pregnancy. Dydrogesterone, a synthetic progestogen, mimics natural progesterone, enhancing endometrial receptivity and reducing miscarriage risk. It has shown effectiveness in improving pregnancy outcomes in women with RPL, particularly those with hormonal imbalances. Unlike other progestins, dydrogesterone has minimal side effects and is well-tolerated. Clinical studies support its role in sustaining early pregnancy until placental progesterone production begins. With its proven safety and efficacy, dydrogesterone remains a key therapeutic option for women struggling with recurrent pregnancy loss.